Installing SCEP 2012 - NIS updates during deployment

During deployment I'm using SCEP installation and update packages a lot. When using the script from Chris Nackers, new definitions can be downloaded automatically each day. Therefore a system is deployed with the latest SCEP update during deployment, and there's less security risk after deployment. Most of time SCEP installation, and antimalware/ antispyware (MPAM) updates goes fine, but Network Inspection System (NIS) updates goes wrong. Errors given are:
-Installation completed with exit code 0x80004005
-Installation failed with error (0x80004005)
-Install Software failed, hr=0x80004005. The operating system reported error 2147500037: Unspecified error

This because you're using the wrong version then. When looking on Microsoft Malware Protection Center, the following is mentioned:
1. Open your security software by double clicking on the icon in the system tray (you may need to click the arrow to see the icon) or, in Windows 8.1, search for Windows Defender:
2. Click the arrow next to Help and choose About:
3. Your software version number is displayed at the line labelled Antimalware Client Version

For version number 4.1.522.0 and above, you must download the Network Realtime Inspection definitions:
-For 32-bit versions of Windows, download 32-bit Network Realtime Inspection definitions
-For 64-bit versions of Windows, download 64-bit Network Realtime Inspection definitions
If you have a version number lower than 4.1.522.0, you must download the Network Inspection Service definitions:
-For 32-bit versions of Windows, download 32-bit Network Inspection Service definitions
-For 64-bit versions of Windows, download 64-bit Network Inspection Service definitions

So yes, there is a difference between Network Realtime Inspection (NRI) and Network Inspection Services (NIS) definitions.

Source: Malware Protection Center

More blogposts on this topic:
Install and update Endpoint Protection (SCEP) during a task sequence